This test can also indicate if you have a hereditary risk of developing other cancers – and therefore what steps you need to take for further screening or monitoring. The TumorNext-HRD test analyses 11 genes in your DNA to give you and your clinician clear indications of whether targeted PARP inhibitor treatment will help you. In effect, it causes tumour cells to die. It involves drugs which block an enzyme used by cancer cells to repair damage to their DNA caused by chemotherapy, but it doesn’t affect healthy cells. Most women who have ovarian cancer have particular gene mutations in their DNA – specifically those in BRCA1 and BRCA2 genes.īut that is not always the case, and if you have a different gene mutation, a new therapy that could help you is PARP inhibitor treatment.
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